Ampreloxetine (hydrochloride)
CAS No. : 1227056-87-2
(Synonyms: TD-9855 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $240 | In-stock |
| 10mg | $390 | In-stock |
| 25mg | $780 | In-stock |
| 50mg | $945 | In-stock |
| 100mg | $1320 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-107128 |
| M.Wt: | 357.80 |
| Formula: | C18H19ClF3NO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma[1]. In Vivo:Ampreloxetine hydrochloride (0.3-60 mg/kg; PO; single dose) is irrespective between plasma concentration and dose level in rat model[1].
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