FLLL32
CAS No. : 1226895-15-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $77 | In-stock |
| 10mg | $110 | In-stock |
| 25mg | $165 | In-stock |
| 50mg | $275 | In-stock |
| 100mg | $495 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100544 |
| M.Wt: | 464.55 |
| Formula: | C28H32O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
FLLL32, a synthetic analog of curcumina, is a JAK2/STAT3 dual inhibitor with anti-tumor activity. FLLL32 can inhibit the induction of STAT3 phosphorylation by IFNα and IL-6 in breast cancer cells[1][2]. IC50 & Target: JAK2/STAT3[1] In Vitro: FLLL32 specifically reduces STAT3 phosphorylation at Tyr705 (pSTAT3) and induces apoptosis at micromolar amounts in human melanoma cell lines and primary melanoma cultures[1].
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