LCL521


CAS No. : 1226851-11-1

1226851-11-1
Price and Availability of CAS No. : 1226851-11-1
Size Price Stock
5mg $350 In-stock
10mg $550 In-stock
50mg $1650 In-stock
100mg $2650 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-103593
M.Wt: 592.77
Formula: C31H52N4O7
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1226851-11-1 :

LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1]. IC50 & Target:ACDase, ASMase[1] In Vitro: LCL521 (1 μM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 μM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 μM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells[1].

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