Omarigliptin
CAS No. : 1226781-44-7
(Synonyms: MK-3102)
| Size | Price | Stock |
|---|---|---|
| 2mg | $61 | In-stock |
| 5mg | $99 | In-stock |
| 10mg | $165 | In-stock |
| 50mg | $495 | In-stock |
| 100mg | $715 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-15981 |
| M.Wt: | 398.43 |
| Formula: | C17H20F2N4O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier dipeptidyl peptidase 4 (DPP-4) inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction[1][2][3].
In Vivo: Omarigliptin (5 mg/kg; p.o.) enhances the intestinal glucagon like peptide-1 and crosses BBB in rats[1].
Omarigliptin (2.5, 5 mg/kg; p.o.; once a week for 8 weeks) shows anti-diabetic activity in STZ-induced diabetic mice[2].
Omarigliptin (5 mg/kg; p.o.; daily for 28 days) shows anti-parkinsonian activity in rats[3].
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