4,4'-Dimethoxybenzil
CAS No. : 1226-42-2
(Synonyms: p-Anisil)
| Size | Price | Stock |
|---|---|---|
| 5g | $7 | In-stock |
| 10g | $13 | In-stock |
| 25g | $25 | In-stock |
| 100g | $69 | In-stock |
| 500g | $344 | In-stock |
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| 2 kg | Get quote | |
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| Cat. No. : | HY-103610 |
| M.Wt: | 270.28 |
| Formula: | C16H14O4 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ mg/mL;DMSO : 50 mg/mL (ultrasonic) |
4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM. IC50 & Target: Ki: 70 nM (hiCE)[1] In Vitro: By reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed[1].
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