Faropenem sodium
CAS No. : 122547-49-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $32 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $130 | In-stock |
| 100mg | $180 | In-stock |
| 500mg | $450 | In-stock |
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| 5 g | Get quote | |
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| Cat. No. : | HY-76260 |
| M.Wt: | 307.30 |
| Formula: | C12H14NNaO5S |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 25 mg/mL (ultrasonic) |
Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis[1][2].
IC50 & Target:Bacterial[1]
In Vitro:Faropenem (0.0015-200 μg/mL, 4-7 days) sodium exhibits antituberculosis activity against M. tuberculosis, with MIC of 1.3 μg/mL (with or without clavulanate)[1].
Faropenem (14C radiolabeled, 1 μCi/μL, 30 min) sodium transports across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1[2].
In Vivo:Faropenem (500 mg/kg, p.o., from days 1 to 7 postinfection) sodium reduces bacterial (M. tuberculosis) load in an murine infection model of acute tuberculosis[1].
Faropenem (10-80 mg/kg/day, i.p., 24 h postchallenge at 4-, 6-, and 12-h intervals for 14 days) sodium demonstrates a high level of activity against B. anthracis in the murine postexposure prophylaxis inhalation model[3].
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