c-Kit-IN-1
CAS No. : 1225278-16-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $92 | In-stock |
| 10mg | $152 | In-stock |
| 25mg | $303 | In-stock |
| 50mg | $486 | In-stock |
| 100mg | $778 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15240 |
| M.Wt: | 489.47 |
| Formula: | C26H21F2N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of <200 nM. IC50 & Target:IC50: <200 nM (c-Met), <200 nM (c-Kit), <2 μM (KDR), <10 μM (PDGFRα), <10 μM (PDGFRβ)[1] In Vitro:c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively[1].
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