Protriptyline (hydrochloride)
CAS No. : 1225-55-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $135 | In-stock |
| 100mg | $200 | In-stock |
| 250mg | $420 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-B0949 |
| M.Wt: | 299.84 |
| Formula: | C19H22ClN |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic) |
Protriptyline hydrochloride is a potent tricyclic antidepressant (TCA). Protriptyline hydrochloride inhibits AChE activity with an IC50 value of 0.06 mM and inhibits Aβ self-assembly. Protriptyline hydrochloride can be used for the study of depression and Alzheimers disease[1][2][3]. In Vitro:Protriptyline hydrochloride (0-70 μM; 24 hours; PC3 cells) causes cytotoxicity in PC3 cells[2]. In Vivo:Protriptyline hydrochloride (10 mg/kg; i.p.; for 21 days; rat model of AD) improves spatial learning and retention memory in STZ treated rats[3].
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