MFZ 10-7
CAS No. : 1224431-15-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $71 | In-stock |
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $850 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103575 |
| M.Wt: | 236.24 |
| Formula: | C15H9FN2 |
| Purity: | >98 % |
| Solubility: | DMSO : 17.86 mg/mL (ultrasonic;warming;heat to 60°C) |
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a Ki of 0.67 nM for rat mGluR5[1]. MFZ 10-7 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC50 & Target:Ki: 0.67 nM (rat mGluR5)[1]
In Vitro:MFZ 10-7 has approximately 1150- and 3000-fold lower affinity for MAO-B (monoamine oxidase-B enzyme) and TXA2 (thromboxane A2 receptor), respectively, compared to mGluR5[1].
In Vivo:MFZ 10-7 can lower oral sucrose self-administration rate but has no effect on total sucrose intake[1].
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- HY-103575
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