Redaporfin
CAS No. : 1224104-08-8
(Synonyms: LUZ11; F2BMet)
| Size | Price | Stock |
|---|---|---|
| 5mg | $380 | In-stock |
| 10mg | $650 | In-stock |
| 25mg | $1350 | In-stock |
| 50mg | $2300 | In-stock |
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| Cat. No. : | HY-17644 |
| M.Wt: | 1135.11 |
| Formula: | C48H38F8N8O8S4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Redaporfin (LUZ11) acts as a potent photosensitizer. Redaporfin causes direct antineoplastic effects as well as indirect immune-dependent destruction of malignant lesions[1]. In Vitro:The combination photodynamic therapy (PDT) with Redaporfin (5μM) induces a reduction in the abundance of several Golgi apparatus (GA) proteins such as Golgi brefeldin A-resistant guanine nucleotide exchange factor 1 (GBF1), golgin subfamily A member 2 (GOLGA2), and galactosyltransferase 1 (GALT1), as well as that of two ER proteins, eukaryotic translation initiation factor 2-alpha (eIF2α) kinase 3 (EIF2AK3) and protein disulfide-isomerase A3 (PDIA3). In contrast, there is no major decrease in mitochondrial import receptor subunit TOM20 homolog (TOMM20) or in the cytoskeleton protein β-actin[1].
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