SAR629
CAS No. : 1221418-42-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $78 | In-stock |
| 10mg | $125 | In-stock |
| 25mg | $246 | In-stock |
| 50mg | $395 | In-stock |
| 100mg | $595 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-118653 |
| M.Wt: | 383.39 |
| Formula: | C20H19F2N5O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2]. In Vitro: SAR629 is a potent dual inhibitory action on MAGL and fatty acid amide hydrolase (FAAH). SAR629 inhibits rodent monoglyceride lipase (MGL) activity at subnanomolar potencies (IC50 values of 1.1 nM and 219 pM in rat and mouse brain membranes, respectively)[1].
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