Propargyl-PEG1-NH2
CAS No. : 122116-12-5
| Size | Price | Stock |
|---|---|---|
| 1g | $32 | In-stock |
| 5g | $125 | In-stock |
| 10g | $249 | In-stock |
| 25g | $465 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-116069 |
| M.Wt: | 99.13 |
| Formula: | C5H9NO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-NH2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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