AMPK-IN-1
CAS No. : 1219739-95-3
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|---|---|---|
| 5mg | $530 | In-stock |
| 10mg | $845 | Get quote |
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| 50mg | $2650 | Get quote |
| 100mg | $3980 | Get quote |
| 200 mg | Get quote | |
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| Cat. No. : | HY-120904 |
| M.Wt: | 431.87 |
| Formula: | C24H18ClN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
AMPK-IN-1 is an activator of AMPK (EC50: 551 nM for isoform α2β2γ1). AMPK-IN-1 leads to eEF2 phosphorylation in a mTORC1-independent way[1][2][3].
In Vitro:AMPK-IN-1 (Compound 991) (5 μM, 60 min) induces phosphorylation of acetyl-coenzyme A carboxylase (ACC) in mouse epitrochlearis muscle ex vivo[1].
AMPK-IN-1 (0-10 μM, 60 min) induces eEF2 phosphorylation in MEF cells, and is mainly mTORC1-independent[1].
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