ROCK-IN-13
CAS No. : 1219727-16-8
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| Cat. No. : | HY-116233 |
| M.Wt: | 334.41 |
| Formula: | C20H22N4O |
| Purity: | >98 % |
| Solubility: |
ROCK-IN-13 is a ROCK2 inhibitor with an IC50 of 8 nM against human ROCK2. ROCK-IN-13 has the potential for use in the research of diseases such as multiple sclerosis, glaucoma, and cardiovascular diseases.
In Vitro:ROCK-IN-13 (Compound D3) (4 h) potently inhibits recombinant human ROCK2, with an IC50 value of 8 nM[1].
ROCK-IN-13 (70 min) weakly inhibits recombinant human PKA, with an experimental IC50 of 3381 nM, and shows 422-fold higher selectivity for ROCK2 than for PKA[1].
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