A-1048400
CAS No. : 1219624-62-0
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| Cat. No. : | HY-120484 |
| M.Wt: | 543.70 |
| Formula: | C36H37N3O2 |
| Purity: | >98 % |
| Solubility: |
A-1048400 is an orally active and selective calcium channel inhibitor with an IC50 value of 1.4 μM for N-type channels, 1.2 μM for T-type channel. A-1048400 inhibits neurotransmitter release and reduces membrane hyperexcitability, exerting potent analgesic activity. A-1048400 is promising for research of neuropathic pain (e.g., pain induced by spinal nerve ligation and chronic constriction injury)[1].
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