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|---|---|---|
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| 500 mg | Get quote | |
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| Cat. No. : | HY-120967 |
| M.Wt: | 668.99 |
| Formula: | C34H73N2O6PS |
| Purity: | >98 % |
| Solubility: |
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, Lysophosphatidic acid analogue, is a LPA3 G-protein-coupled receptor agonist. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% selectively activates LPA3 G-protein-coupled receptor to trigger downstream cellular signaling events. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% induces calcium, IL-6 release in cancer cells and activates MAPK and Akt signaling pathways. (2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98% can be used for the research of ovarian cancer[1].
In Vitro:(2S)-OMPT (0.001-10000 nM) (triethylamine), in ethanol:chloroform (1:1), 98% induces calcium release in human ovarian cancer OVCAR3 cells with an EC50 of 9.0 nM[1].
(2S)-OMPT (0.01-1 μM) (triethylamine), in ethanol:chloroform (1:1), 98% activates Akt and MAPK phosphorylation in human ovarian cancer OVCAR3 cells[1].
(2S)-OMPT (0.01-10 μM) (triethylamine), in ethanol:chloroform (1:1), 98% induces IL-6 release in human ovarian cancer OVCAR3 cells[1].
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