CP-31398 (dihydrochloride)
CAS No. : 1217195-61-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $41 | In-stock |
| 5mg | $82 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $207 | In-stock |
| 50mg | $330 | In-stock |
| 100mg | $528 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-18343A |
| M.Wt: | 435.39 |
| Formula: | C22H28Cl2N4O |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic) |
CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53[1][2][3].
In Vitro: CP-31398 (36.75 μM, 16 h) induces p21 in p53-mutant cells[1].
CP-31398 (15 μg/mL, 20 hours) could induce apoptosis and cell cycle arrest in SW480 cells[2].
In Vivo: CP-31398 (100 mg/kg, orally) exhibits significant anti-tumor activity in mice models[1].
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