DMCM (hydrochloride)
CAS No. : 1215833-62-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $95 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $590 | In-stock |
| 100mg | $850 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100369A |
| M.Wt: | 350.80 |
| Formula: | C17H19ClN2O4 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic);DMSO : 10 mg/mL (ultrasonic) |
DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 receptors, respectively[1]. IC50 & Target: Ki: 10 nM (GABAA α1 receptor), 13 nM (GABAA α2 receptor), 7.5 nM (GABAA α3 receptor), 2.2 nM (GABAA α5 receptor)[1] In Vivo: DMCM has potent convulsant, proconvulsant and anxiogenic properties in vivo. DMCM (20-60 mg/kg; i.p.) produces modest anxiolytic-like effects in γ2I77 mice[2].
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