Cyprodinil
CAS No. : 121552-61-2
(Synonyms: CGA-219417)
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| Cat. No. : | HY-116214 |
| M.Wt: | 225.29 |
| Formula: | C14H15N3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens[1][2][3].
In Vitro:Cyprodinil can inhibit the growth of B. cinerea, P. herpotrichoides and H. oryzae in amino acid-free medium, with IC50 values of 0.44, 4.8 and 0.03 µM respectively[1].
Cyprodinil (0.64 nM-50 μM; 24 h) exhibits anti-androgenic activity (IC20: 15.1 μM) in MDA-kb2 cells, and androgenic activity (EC20: 1.91 μM) in the absence of DHT. In addition, it also has certain cytotoxicity[2].
Cyprodinil (0-20 μM; 0-15 h) can increase the protein expression of CYP1A1 in a dose-dependent manner in HO23 and Hepa-1c1c7 cells[3].
Cyprodinil (0-20 μM; 5-20 min) can induce the phosphorylation of ERK1/2 in a variety of cells[3].
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