Lauroyl PEG-32 glycerides


CAS No. : 121548-04-7

121548-04-7
Price and Availability of CAS No. : 121548-04-7
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50g $80 In-stock
100g $130 In-stock
500g $320 In-stock
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Cat. No. : HY-Y1892
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: Ethanol : 100 mg/mL (ultrasonic)
Introduction of 121548-04-7 :

Lauroyl PEG-32 glycerides is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery. In Vivo:Lauroyl PEG-32 glycerides is a potential and safe absorption enhancer for improving the absorption of poorly absorbable drugs including insulin and calcitonin by pulmonary delivery. It is found that pulmonary absorptions of FD4, FD10 and FD70 are enhanced in different degree by Lauroyl PEG-32 glycerides in a concentration-dependent manner, and the maximal absorption-enhancing effect is obtained when the concentration of Lauroyl PEG-32 glycerides reaches to 2.0% (w/v). It is also found that the absorption enhancing ability of Lauroyl PEG-32 glycerides is correlated with the molecular weight of model drugs, and the highest absorption enhancement ratio of Lauroyl PEG-32 glycerides is observed when the molecular weight of model drugs reaches to nearly 10000 Da[1].

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