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|---|---|---|
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| Cat. No. : | HY-122638 |
| M.Wt: | 375.44 |
| Formula: | C21H26FNO4 |
| Purity: | >98 % |
| Solubility: |
MRT2000769 is a Kir7.1 inhibitor with an IC50 of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage[1]. In Vitro:MRT2000769 (1.1-3.5 μM) potently inhibits recombinant Kir7.1 channels expressed in Chinese hamster ovary cells, with an IC50 of 2 μM[1]. In Vivo:MRT2000769 induces persistent contractions in the uterine muscle of mice on gestational day 15.
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