MRT2000769


CAS No. : 1214573-32-6

1214573-32-6
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Cat. No. : HY-122638
M.Wt: 375.44
Formula: C21H26FNO4
Purity: >98 %
Solubility:
Introduction of 1214573-32-6 :

MRT2000769 is a Kir7.1 inhibitor with an IC50 of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage[1]. In Vitro:MRT2000769 (1.1-3.5 μM) potently inhibits recombinant Kir7.1 channels expressed in Chinese hamster ovary cells, with an IC50 of 2 μM[1]. In Vivo:MRT2000769 induces persistent contractions in the uterine muscle of mice on gestational day 15.

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