WZ-3146
CAS No. : 1214265-56-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $61 | In-stock |
| 5mg | $130 | In-stock |
| 10mg | $230 | In-stock |
| 50mg | $650 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-12001 |
| M.Wt: | 464.95 |
| Formula: | C24H25ClN6O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively. IC50 & Target: IC50: 2 nM (EGFRL858R), 2 nM (EGFRL858R/T790M), 5 nM (EGFRE746_A750), 14 nM (EGFRE746_A750/T790M), 66 nM (EGFR) [1] In Vitro: WZ3146 is a novel EGFR inhibitor, suppresses the growth of EGFR T790M containing cell lines and inhibits EGFR phosphorylation[1].
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