Jarin-1
CAS No. : 1212704-51-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $90 | In-stock |
| 5mg | $250 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $800 | In-stock |
| 50mg | $1280 | In-stock |
| 100mg | $2050 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-115521 |
| M.Wt: | 471.55 |
| Formula: | C28H29N3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants[1][2]. IC50 & Target: Jasmonic acid-amido synthetase (JAR1)[1][2] In Vitro: A higher redness of strawberry fruit skin and anthocyanin content in MeJA-treated fruits with respect to Jarin-1-treated ones concomitant with an upregulation of FaANS and FaUFGT genes is found. Inversely, the proanthocyanidin (PA) content was higher in Jarin-1- and MeJA + Jarin-1-treated than in MeJA-treated fruits. MeJA + Jarin-1 treatment resulted in an upregulation of FaANR and associated transcription factors such as FabHLH33 and FaMYB9/11 along with FaJMT and FaJAR1.2. JA-responsive elements in the promoter regions of FaMYB1/9/10/11 genes is found. PA biosynthesis-related genes can be upregulated by the application of Jarin-1 to MeJA-treated fruit, thus increasing PA accumulation in strawberry[1].
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