CBK289001
CAS No. : 1212663-24-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $560 | In-stock |
| 10mg | $900 | In-stock |
| 25mg | $1800 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-124663 |
| M.Wt: | 396.40 |
| Formula: | C19H20N6O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively[1].
In Vitro: Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 µM or 100 µM[1].
CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells[1].
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