[Ala1,3,11,15]-Endothelin (53-63)
CAS No. : 121204-87-3
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| Cat. No. : | HY-P1019 |
| M.Wt: | 2367.67 |
| Formula: | C109H163N25O32S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction[1] IC50 & Target:IC50 for ETB: 0.61 nM (Bronchus); 0.61 nM (Lung); 0.33 nM (Cerebellum); 2200 nM (VSMC)[1] In Vitro:[Ala1,3,11,15]-Endothelin (53-63) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1].
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