Ertugliflozin
CAS No. : 1210344-57-2
(Synonyms: PF-04971729)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $70 | In-stock |
| 25mg | $98 | In-stock |
| 50mg | $120 | In-stock |
| 100mg | $170 | In-stock |
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| Cat. No. : | HY-15461 |
| M.Wt: | 436.88 |
| Formula: | C22H25ClO7 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. Has the potential for the treatment of type 2 diabetes mellitus[2]. IC50 & Target: IC50: 0.877 nM (h-SGLT2)[1]. In Vitro: Ertugliflozin (PF-04971729) demonstrates >2000-fold selectivity for SGLT2 inhibition (relative to SGLT1) in vitro[3]. In Vivo: Ertugliflozin (PF-04971729) reveals a concentration-dependent glucosuria after oral administration to rats[3].
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