[Rh(cod)Cl]2
CAS No. : 12092-47-6
(Synonyms: Chloro(1,5-cyclooctadiene)rhodium(I) dimer)
| Size | Price | Stock |
|---|---|---|
| 100mg | $39 | In-stock |
| 250mg | $87 | In-stock |
| 1g | $334 | In-stock |
| 5g | $1663 | In-stock |
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| 50 g | Get quote | |
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| Cat. No. : | HY-Y1094 |
| M.Wt: | 493.08 |
| Formula: | C16H24Cl2Rh2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
[Rh(cod)Cl]2 (Chloro (1,5-cyclooctadiene) rhodium (I) dimer) is an organometallic rhodium (I) dimer precursor and platelet aggregation inhibitor. [Rh(cod)Cl]2 inhibits PAF-induced aggregation in washed rabbit platelets. [Rh(cod)Cl]2 inhibits aggregation induced by PAF, Thrombin, ADP and Collagen in human platelet-rich plasma. [Rh(cod)Cl]2 acts as a catalyst precursor for the hydrogenation of aromatic hydrocarbons, phenols, olefins and BINOL derivatives. [Rh(cod)Cl]2 is used in the research of cardiovascular diseases such as thromboinflammation-related disorders, tumor metastasis and atherosclerosis[1][2].
In Vitro:[Rh(cod)Cl]2 inhibits washed rabbit platelet aggregation induced by platelet-activating factor (PAF), with an IC50 of 5.2 μM[1].
[Rh(cod)Cl]2 inhibits PAF-induced aggregation of human platelet-rich plasma, with an IC50 of 43.3 μM[1].
[Rh(cod)Cl]2 inhibits thrombin (HY-114164)-induced aggregation of human platelet-rich plasma with an IC50 of 16.7 μM[1].
[Rh(cod)Cl]2 inhibits ADP (HY-W010918)-induced aggregation of human platelet-rich plasma with an IC50 of 162 μM[1].
[Rh(cod)Cl]2 inhibits collagen (HY-NP003)-induced aggregation of human platelet-rich plasma, with an IC50 of 69.8 μM[1].
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