VU 0365114
CAS No. : 1208222-39-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $154 | In-stock |
| 50mg | $484 | In-stock |
| 100mg | $759 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-107651 |
| M.Wt: | 397.35 |
| Formula: | C22H14F3NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 77.5 mg/mL |
VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells[1][2][3].
IC50 & Target:EC50: 2.7 μM (mAChR M5)[1].
In Vitro:VU 0365114 (10 μM) increases insulin secretion stimulated by ACh in human β-cells[2].
VU 0365114 (10 μM) does not alter somatostatin secretion stimulated by ACh in human β-cells[2].
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