Bozepinib
CAS No. : 1207993-83-6
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| Cat. No. : | HY-118032 |
| M.Wt: | 521.33 |
| Formula: | C20H14Cl2N6O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Bozepinib is a PKR (RNA-dependent protein kinase) activator and potently inhibits the HER-2 signaling pathway as well as JNK and ERK kinases. Bozepinib induces PKR-mediated apoptosis and synergizes with IFNα to trigger apoptosis, autophagy and senescence. Bozepinib also demonstrates in vivo antitumor and antimetastatic efficacy in xenografted nude mice[1][2].
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