Broflanilide
CAS No. : 1207727-04-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $230 | In-stock |
| 50mg | $750 | In-stock |
| 100mg | $1250 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-108689 |
| M.Wt: | 663.28 |
| Formula: | C25H14BrF11N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM[1]. In Vitro: Broflanilide is an insecticide and metabolized to desmethyl-broflanilide, which is a potent and selective antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM. Desmethyl-broflanilide shows weak activity against human GABAA α1β2γ2 receptor, the mammalian GABAA α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC50s of >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM)[1].
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