(8R,9S)-Talazoparib


CAS No. : 1207456-00-5

(Synonyms: (8R,9S)-BMN-673; (8R,9S)-LT-673)

1207456-00-5
Price and Availability of CAS No. : 1207456-00-5
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5mg $70 In-stock
10mg $100 In-stock
50mg $250 In-stock
100mg $400 In-stock
200mg $550 In-stock
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Cat. No. : HY-16106A
M.Wt: 380.35
Formula: C19H14F2N6O
Purity: >98 %
Solubility: DMSO : ≥ 50 mg/mL
Introduction of 1207456-00-5 :

(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC50 of 144 nM[1]. IC50 & Target:IC50: 144 nM (PARP-1)[1] In Vitro: (8R,9S)-Talazoparib shows an EC50 of 864 nM in cellular PARylation assay[1].
(8R,9S)-Talazoparib shows an EC50 of 1135 nM for Capan-1 cells (BRCA2 mutant)[1].

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