GLPG0634 analog
CAS No. : 1206101-20-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $180 | In-stock |
| 50mg | $600 | In-stock |
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| Cat. No. : | HY-13961 |
| M.Wt: | 410.43 |
| Formula: | C23H18N6O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 53 mg/mL |
GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3[1].
In Vitro: GLPG0634 analog (Compoun 176) inhibits JAK-STAT signaling and OSM/IL-lβ signaling with both EC50 values of 101-500 nM[1].
GLPG0634 analog shows microsomal stability of 76%-100% in rat and human[1].
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