BML-278
CAS No. : 120533-76-8
| Size | Price | Stock |
|---|---|---|
| 250mg | $5 | In-stock |
| 1g | $18 | In-stock |
| 5g | $89 | In-stock |
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| 50 g | Get quote | |
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| Cat. No. : | HY-W025074 |
| M.Wt: | 391.46 |
| Formula: | C24H25NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
BML-278 is a SIRT1 activator (EC150: 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts[1][2].IC50 & Target:SIRT1[1].
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