EMD 53998


CAS No. : 120223-04-3

120223-04-3
Price and Availability of CAS No. : 120223-04-3
Size Price Stock
5mg $620 In-stock
10mg $990 In-stock
25mg $1980 In-stock
50mg $3170 In-stock
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Cat. No. : HY-106844
M.Wt: 425.50
Formula: C22H23N3O4S
Purity: >98 %
Solubility:
Introduction of 120223-04-3 :

EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE III) and a calcium sensitizer. EMD 53998 increases myocardial contractility, reduces energy consumption and the risk of inducing arrhythmias[1]. In Vitro:EMD 53998, a racemic thiadiazinone derivative, is a potent Ca2+-sensitizer. EMD 53998 (0.1-100 μM) increases force of contraction (FOC) in a concentration-dependent manner. EMD 53998 increases force of contraction in human myocardium via sensitizing of the contractile proteins towards Ca2+ and by inhibition of phosphodiesterase III-isoenzymes[12].

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