MK-3328


CAS No. : 1201323-97-8

1201323-97-8
Price and Availability of CAS No. : 1201323-97-8
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1mg $571 In-stock
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Cat. No. : HY-100275
M.Wt: 268.25
Formula: C14H9FN4O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1201323-97-8 :

MK-3328 is a β-Amyloid ligand, which exhibits high binding potency with an IC50 of 10.5 nM. MK-3328 is capable of being labelled with 18F for positron emission tomography (PET) imaging[1][2]. IC50 & Target:IC50: 10.5 nM (β-Amyloid)[1] In Vitro:MK-3328 exhibits amyloid binding potency balanced with low levels of nonspecific binding[1]. In Vivo:In vivo, [18F]MK-3328 demonstrates favorable kinetics, exhibiting high brain uptake and good washout in normal rhesus monkey positron emission tomography (PET) imaging studies[1].

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