Peroxy Orange 1


CAS No. : 1199576-10-7

(Synonyms: PO1)

1199576-10-7
Price and Availability of CAS No. : 1199576-10-7
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1mg $185 In-stock
5mg $460 In-stock
10mg $738 In-stock
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Cat. No. : HY-103469
M.Wt: 521.41
Formula: C32H32BNO5
Purity: >98 %
Solubility: DMSO : 5.21 mg/mL (ultrasonic;warming)
Introduction of 1199576-10-7 :

Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye[1][2]. In Vitro: Peroxy Orange 1 is a high sensitive fluorescent probe for H2O2 that emits orange fluorescence with excitation and emission wavelengths of 543 nm and 565 nm[1].
Peroxy Orange 1 contains a boronate group, which would be oxidized to a phenol group with bright orange fluorescence. This boronate-phenol conversion mechanism does not react with other ROS (such as superoxide anions, NO, etc.), and ensures the high selectivity of Peroxy Orange 1 for H2O2[1]. Peroxy Orange 1 exhibits good cell permeability that can detect H2O2 in living cells without significant toxicity in cells[1].
Peroxy Orange 1 is compatible with common green fluorescent probes (such as GFP, APF, etc.) and can be used for multicolor imaging experiments[1].

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