TGR5 Receptor Agonist
CAS No. : 1197300-24-5
(Synonyms: CCDC)
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $165 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $560 | In-stock |
| 100mg | $900 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-14229 |
| M.Wt: | 361.22 |
| Formula: | C18H14Cl2N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 48 mg/mL |
TGR5 Receptor Agonist (CCDC), a potent Takeda G protein-coupled receptor 5 (TGR5; GPCR19) agonist, shows improved potency in the U2-OS cells and melanophore cells with pEC50s of 6.8 and 7.5, respectively. TGR5 Receptor Agonist can induce peripheral and central hypersensitivity to bladder distension in mice, and increase intracellular Ca2+ concentration. TGR5 Receptor Agonist can also reduces food intake and improves insulin responsiveness, in diet-induced obese mice. TGR5 Receptor Agonist can be used to research diabetes, bladder hypersensitivity and anti-obesity[1][2][3][4].
IC50 & Target: TGR5[1]
In Vivo: TGR5 Receptor Agonist (CCDC) activates directly a sub-population of bladder-innervating dorsal root ganglia (DRG) neurons and a small percentage of non-neuronal cells in Trpv1-/- mice[2].
TGR5 Receptor Agonist (CCDC) (2 or 5 μg; ICV) reduces food intake and body weight in diet-induced obese mice[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- TGR5 Receptor Agonist
- Cat. No.:
- HY-14229
- Quantity:
Your information is safe with us.