Eliprodil
CAS No. : 119431-25-3
(Synonyms: SL-820715)
| Size | Price | Stock |
|---|---|---|
| 5mg | $56 | In-stock |
| 10mg | $88 | In-stock |
| 25mg | $200 | In-stock |
| 50mg | $310 | In-stock |
| 100mg | $480 | In-stock |
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| Cat. No. : | HY-12881 |
| M.Wt: | 347.85 |
| Formula: | C20H23ClFNO |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). IC50 value: Target: NR2B-NMDA antagonist Human N-type Ca2+ channel currents were inhibited by ifenprodil and eliprodil with IC50 values of 50 microM and 10 microM respectively whereas P-type Ca2+ channel currents were inhibited reversibly by ifenprodil and eliprodil with approximate IC50 values of 60 microM and 9 microM respectively. eliprodil (1 microm) produced a moderate reverse rate-dependent prolongation of the action potential duration (7.4+/-1.5, 8.9+/-2.1 and 9.9+/-1.8% at cycle lengths of 300, 1000 and 5000 ms, respectively; n=9).
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- Eliprodil
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- HY-12881
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