Loureirin A
CAS No. : 119425-89-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $59 | In-stock |
| 10mg | $89 | In-stock |
| 25mg | $177 | In-stock |
| 50mg | $266 | In-stock |
| 100mg | $400 | In-stock |
| 250mg | $800 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-N1505 |
| M.Wt: | 286.32 |
| Formula: | C17H18O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 86.6 mg/mL |
Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. IC50 & Target:Akt[1] In Vitro: Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM[1].
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