Avibactam (sodium)
CAS No. : 1192491-61-4
(Synonyms: NXL-104)
| Size | Price | Stock |
|---|---|---|
| 5mg | $72 | In-stock |
| 10mg | $96 | In-stock |
| 50mg | $156 | In-stock |
| 100mg | $228 | In-stock |
| 200mg | $312 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-14879A |
| M.Wt: | 287.23 |
| Formula: | C7H10N3NaO6S |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : ≥ 30 mg/mL |
Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1].
IC50 & Target: IC50: 5 nM (CTX-M-15), 8 nM (TEM-1)[1]
In Vitro: Avibactam is a molecule with little antibacterial activity, that inhibits class A and C β-lactamases, but not metallo types and Acinetobacter OXA carbapenemases[2].
Ceftazidime (HY-B0593)-Avibactam (0-256 mg/L) inhibits 16 blaKPC-2 positive and 1 of blaOXA-232 positive Klebsiella pneumonia growth with MIC50 and MIC90 for both 8?mg/L[4].
In Vivo: Ceftazidime-Avibactam (0.375?mg/g; s.c.; q8h for 10 days) has a significant effect on the bacteria and led to a certain therapeutic efficacy in K. pneumoniae strain Y8 infected mouse model[3].
Avibactam (64 mg/kg; s.c.; once) shows mean estimated half-life in plasma in the terminal phase of 0.24 h in Pseudomonas aeruginosa infected neutropenic mice with lung infection[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Avibactam (sodium)
- Cat. No.:
- HY-14879A
- Quantity:
Your information is safe with us.