LY255582


CAS No. : 119193-09-8

119193-09-8
Price and Availability of CAS No. : 119193-09-8
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Cat. No. : HY-118949
M.Wt: 345.52
Formula: C22H35NO2
Purity: >98 %
Solubility: DMSO : 15 mg/mL (ultrasonic;warming)
Introduction of 119193-09-8 :

LY255582 is a pan-opioid antagonist and has high affinity for mu, delta, and kappa receptors (Ki: 0.4 nM, 5.2, 2.0 nM respectively). LY255582 can decrease food intake and body weight. LY255582 can be used for the research of obesity[1][2][3][4]. In Vitro:LY255582 (40 μM, 24-72 h) reduces cell viability of Huh7 and MHCC-97H cells[5].
In Vivo:LY255582 (100 μg, i.c.v.) reduced food intake in rats[1].
LY255582 (15 mg/kg, s.c., once daily) decreases food intake and body weight gain of fed obese Zucker rats[4].

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