Bisindolylmaleimide IV


CAS No. : 119139-23-0

(Synonyms: Arcyriarubin A)

119139-23-0
Price and Availability of CAS No. : 119139-23-0
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10mg $112 In-stock
25mg $226 In-stock
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100mg $440 In-stock
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Cat. No. : HY-108254
M.Wt: 327.34
Formula: C20H13N3O2
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 119139-23-0 :

Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM)[1]. Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM[2]. In Vitro: Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC50 of 0.1 μM in 1 % DMSO, while the IC50 of 0.55 μM in 10 % DMSO[1].

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