Amino-PEG5-C2-acid
CAS No. : 1191078-74-6
| Size | Price | Stock |
|---|---|---|
| 50mg | $24 | In-stock |
| 100mg | $31 | In-stock |
| 250mg | $47 | In-stock |
| 1g | $77 | In-stock |
| 5g | $366 | Get quote |
| 10 g | Get quote | |
| 50 g | Get quote | |
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| Cat. No. : | HY-115384 |
| M.Wt: | 309.36 |
| Formula: | C13H27NO7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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- Amino-PEG5-C2-acid
- Cat. No.:
- HY-115384
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