PSI-7976
CAS No. : 1190308-01-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $420 | In-stock |
| 5mg | $980 | In-stock |
| 10mg | $1550 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-15005A |
| M.Wt: | 529.45 |
| Formula: | C22H29FN3O9P |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. In Vitro: PSI-7851 is a mixture of two diastereoisomers, PSI-7976 and PSI-7977, with PSI-7977 being the more active inhibitor of HCV RNA replication in the HCV replicon assay. Carboxylesterase 1 (CES1) preferentially hydrolyzes PSI-7976 over PSI-7977. The kinetic data also indicates that PSI-7976 is a better substrate for CES1 than for cathepsin A (CatA)[1]
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