Delta-Tocopherol


CAS No. : 119-13-1

119-13-1
Price and Availability of CAS No. : 119-13-1
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Cat. No. : HY-113026
M.Wt: 402.65
Formula: C27H46O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 119-13-1 :

Delta-Tocopherol is an isomer of Vitamin E[1]. In Vitro:Delta-Tocopherol (0-100 μM, 96 h) inhibits cell growth and induces apoptosis in human prostate cancer LNCaP cells[2].
Delta-Tocopherol (0-100 μM, 24 h) inhibits DHT (10 nM) -induced androgen receptor activation and its downstream target PSA in CWR-22Rv1/AR cells[2].
Delta-Tocopherol (10 μM, 1-4 days) decreases estrogen induced cyclin D1 and c-Myc levels in MCF-7 cells and MDA-MB-231 cells[3].
In Vivo:Delta-Tocopherol (0.2% supplemented in diet, 28 weeks) inhibits the development of prostate adenocarcinoma in Ptenp−/− mice[1].
Delta-Tocopherol (0.2% supplemented in diet, 5 weeks) inhibits tumor growth in MCF-7 xenograft model[1].

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