(E)-KN-93 (phosphate)


CAS No. : 1188890-41-6

1188890-41-6
Price and Availability of CAS No. : 1188890-41-6
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25mg $200 In-stock
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Cat. No. : HY-110140
M.Wt: 599.03
Formula: C26H32ClN2O8PS
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1188890-41-6 :

(E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 μM and 3 μM, for CaMKIIδ monomer and CaMKIIδ dodecamer. (E)-KN-93 phosphate binds competitively with Ca2+/CaM, and disrupts their interaction with CaMK II, and thus inhibits the CaMK II activation[1].

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