PI3K/mTOR-IN-23 (dihydrochloride)
CAS No. : 1188890-32-5
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| 5mg | $590 | In-stock |
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| Cat. No. : | HY-109633A |
| M.Wt: | 386.30 |
| Formula: | C16H17Cl2N3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming) |
PI3K/mTOR-IN-23 dihydrochloride is a dual inhibitor of PI3K and mTOR with IC50 values of 49 and 41 nM. PI3K/mTOR-IN-23 dihydrochloride inhibits cancer cells proliferation[1].
In Vitro:PI3K/mTOR-IN-23 (Compound 1) dihydrochloride acts as a dual inhibitor of mTOR and PI3K-α in recombinant enzyme assays, with an mTOR IC50 of 49 nM, a PI3K-α IC50 of 41 nM[1].
PI3K/mTOR-IN-23 dihydrochloride inhibits LNCaP cell proliferation with an IC50 of 1300 nM[1].
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