NBQX
CAS No. : 118876-58-7
(Synonyms: FG9202)
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $675 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15068 |
| M.Wt: | 336.28 |
| Formula: | C12H8N4O6S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 75 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C);1 M NaOH : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity[1].
IC50 & Target: AMPA receptor[1]
In Vitro: NBQX (FG9202) has a high affinity for AMPA and kainate binding sites with little or no affinity for the glutamate recognition site on the NMDA receptor complex[1].
In Vivo: NBQX (FG9202; 20 mg/kg, i.p.; for 3 days) decreases seizures induced by PTZ[2].
NBQX is neuroprotective in a focal ischaemia model in the rat when given as an i.v. bolus dose of 30 mg/kg at the time of MCA occlusion and again at 1 h post occlusion[1].
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