Valecobulin
CAS No. : 1188371-47-2
(Synonyms: CKD-516)
| Size | Price | Stock |
|---|---|---|
| 5mg | $280 | In-stock |
| 10mg | $450 | In-stock |
| 50mg | $1350 | In-stock |
| 100mg | $1850 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-13598 |
| M.Wt: | 536.60 |
| Formula: | C26H28N6O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Valecobulin (CKD516) is a valine prodrug of (S516) and a vascular disrupting agent (VDA). Valecobulin is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors[1][2]. IC50 & Target: β-tubulin polymerization[1]. In Vivo: Valecobulin (5 mg/kg; intraperitoneal injection; administered on days 2, 6, 10, and 14; male BALB/C nu/nu mice) treatment shows markedly antitumor efficacy in various human tumor xenograft models[1].
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