Cerebrocrast
CAS No. : 118790-71-9
(Synonyms: IOS-1.1212)
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| 5mg | $820 | Get quote |
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| Cat. No. : | HY-106808 |
| M.Wt: | 511.56 |
| Formula: | C26H35F2NO7 |
| Purity: | >98 % |
| Solubility: |
Cerebrocrast (IOS-1.1212) is a 1,4-dihydropyridine (DHP) derivative. Cerebrocrast has a high affinity for the membrane lipid bilayer and it can easily penetrate the blood-brain barrier and incorporate into the plasma and organelle membranes, including those of mitochondria. Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria. Cerebrocrast also exhibits neuroprotective and cognition enhancer properties[1][2]. In Vitro:Cerebrocrast (25 μM) inhibits the inner mitochondrial anion channel with an IC50 value of 10.5 ± 2.0 μM in rat liver mitochondria[1].
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